Uric Acid Assay Kit (UA)
For the in vitro quantitative determination of Uric Acid in serum.
Uric acid is end product of the purine metabolism. In gout, the most common complication of hyperuricemia, increased serum levels of uric acid lead to formation of monosodium urate crystals around the joints. Further causes of elevated blood concentrations of uric acid are renal diseases with decreased excretion of waste products, starvation, drug abuse and increased alcohol consume as well as use of certain medicaments. High uric acid levels also constitute a indirect risk factor for coronary heart disease. Hypouricemia is seldom observed and associated with rare hereditary metabolic disorders.
Uric acid is oxidized to allantoin by uricase. The generated hydrogen peroxide reacts with TBHBA and 4- aminoantipyrine to a quinone dye. The absorption of the solution of this dye is proportional to the concentration of uric acid in the sample.
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