TruQuick™ CMV IgM
TruQuick CMV IgM is a lateral flow immunoassay for the qualitative detection of IgM antibodies to CMV in serum or plasma to aid in the diagnosis of CMV infection.
Cytomegalovirus is a herpes virus. It is a leading etiological agent for congenital abnormalities and complications among those who receive massive blood transfusions and immunosuppressive therapy. About half of pregnant women who contract a primary infection spread the disease to their fetus.1-3 Infection during pregnancy may cause mental retardation, blindness, and/or deafness of the neonate. The detection of anti-CMV IgM antibodies enables effective diagnosis of acute or recent CMV infection. TruQuick CMV IgM is a rapid chromatographic immunoassay for the qualitative detection of IgM antibodies to CMV in serum or plasma specimens.
- Bring the pouch to room temperature before opening it. Remove the Test Cassette from the sealed pouch and use it as soon as possible. Best results will be obtained if the assay is performed within one hour.
- Place the Test Cassette on a clean and level surface. Hold the dropper vertically, draw the specimen about 1 cm above the upper end of the nozzle as shown in illustration below. Transfer 1 full drop (approx. 20 μL) of specimen to the sample well, then add two drops of Buffer (approximately 80 μL) and start the timer. See the illustration below.
- Wait for the colored line(s) to appear. The result should be read at 15 minutes. Do not interpret results after 20 minutes.
- Starr SE, Friedman HM. Human CMV. Chapter 65. In Manual of Clin. Microbiol., 4th ed., Lennett EH, et al. ed. Am. Soc. Microbiol. 1985;pp. 771-719.
- Jor MC. Latent infection and the elusive cytomegalovirus. Rev. Infect. Dis. 1983;5:205-215.
- Starr SE. Cytomegalovirus. Ped. Clin. N. Am. 1979;26:282-293.