Troponin I Human ELISA
Troponin I consists of 181-211 amino acid residues, and the cardiac isoform is larger due to the presence of an additional N-terminal peptide which has a biologically important function in the interactions of troponin I and troponin C. The main function of troponin I is the inhibition of actomyosin ATPase activity.
Cardiac troponin I and T are sensitive biomarkers of myocardial injury and have become central to the diagnosis of myocardial infarction. They are elevated in many clinical syndromes associated with direct myocardial injury, myocardial ischemia, or ventricular strain. They are also released in a number of clinical situations in which thrombotic complications of coronary artery disease. These situations include conditions like pulmonary embolism, sepsis, myocarditis, and acute stroke.
Research topic
Cardiovascular disease
Type
Sandwich ELISA, Biotin-labelled antibody
Applications
Serum, Cell lysate, Plasma
Storage/Expiration
Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
Calibration Curve
Calibration Range
0–25 ng/ml
Limit of Detection
0.38 ng/ml
Intra-assay (Within-Run)
n = 6; CV = 6.1%
Inter-assay (Run-to-Run)
n = 3; CV = 2.8%
– Alghadir AH, Gabr SA. Efficacy of Rhus coriaria (sumac) juice in reducing muscle pain during aerobic exercise. Physiology International (Acta. 103 (2)