ToRCH IgM Combo
TruQuick ToRCH IgM Combo is a rapid chromatographic immunoassay for the qualitative detection of IgM antibodies to Toxoplasma gondii (Toxo), Rubella virus (Rubella), Cytomegalovirus (CMV), and Herpes simplex virus 1/2 (HSV 1/2) in serum or plasma to aid in the diagnosis of ToRCH.
ToRCH is an acronym for a group of infectious diseases that, while infecting the pregnant women, may cause birth defects in their newborns.1 ToRCH stands for four different infections that can adversely affect a pregnant woman and the fetus or newborn often leading to abortion. The infections usually cause few, if any, symptoms in the pregnant woman, but pose greater risks of serious birth defects for neonates. Infections caused by ToRCH is the major cause of BOH (Bad Obstetric History).2 Risks are severe if the mother gets the infection in the first trimester as the baby’s organs start to form in this stage. General symptoms include premature birth, growth retardation, neurological abnormalities, and damage of the eye, liver, heart and ear as well as bone lesions. Microcephaly, hydrocephaly, seizures and psychomotor retardation accompany these malformations.
- Bring the pouch to room temperature before opening it. Remove the Test Cassette from the sealed pouch and use it as soon as possible. Best results will be obtained if the assay is performed within one hour
- Place the Test Cassette on a clean and level surface. Hold the dropper vertically, draw the specimen about 1 cm above the upper end of the nozzle as shown in illustration below. Transfer 1 full drop (approx. 20 μL) of specimen to each sample well, then add 2 drops of Buffer (approximately 80 μL) to each sample well and start the timer. See the illustration below.
- Wait for the colored line(s) to appear. The result should be read at 15 minutes. Do not interpret results after 20 minutes.
- Bring the pouch to room temperature before opening it. Remove the Test Cassette from the sealed pouch and use it as soon as possible. Best results will be obtained if the assay is performed within one hour
- Place the Test Cassette on a clean and level surface. Hold the dropper vertically, draw the specimen about 1 cm above the upper end of the nozzle as shown in illustration below. Transfer 1 full drop (approx. 20 μL) of specimen to each sample well, then add 2 drops of Buffer (approximately 80 μL) to each sample well and start the timer. See the illustration below.
- Wait for the colored line(s) to appear. The result should be read at 15 minutes. Do not interpret results after 20 minutes.