Myeloperoxidase Assay Kit (MPO)

For the in vitro quantitative determination of Myeloperoxidase in serum or plasma.

Regulatery Status: CE

Product Catalog Number Packaging Method/Format
Product Catalog No: Kit (80 Ml) Pack Size: GS251X Pack Size: R1:1×60 ml
R2:1×20 ml
Pack Size: Immunoturbidimetric
Product Catalog No: Kit (80 Ml) Pack Size: GB250X Pack Size: R1:1×60 ml
R2:1×20 ml
Product Catalog No: Kit (80 Ml) Pack Size: GX251X Pack Size: R1:1×60 ml
R2:1×20 ml
Product Catalog No: Kit (60 Ml) Pack Size: GT251X Pack Size: R1:1×45 ml
R2:1×15 ml
Product Catalog No: Kit (60 Ml) Pack Size: GH251X Pack Size: R1:1×45 ml
R2:1×15 ml
Product Catalog No: Kit (122.4 Ml) Pack Size: GD251X Pack Size: R1:24×3.8 ml
R2:12×2.6 ml
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Product Features

Myeloperoxidase (MPO) is a haematin protein in leukocytes, It is linked to both inflammation and oxidative stress by its location in leukocytes and its role in catalyzing the formation of oxidizing agents. Recentevidence suggests that MPO activity precipitates atherogenesis. Measurement of MPO in plasma or serum may therefore contribute to cardiovascular disease (CVD) risk stratification and other chronic disease.

Assay Principle

Myeloperoxidase in sample reacts with antibodyspecific for human Myeloperoxidase coated by latex particals. The formation of the antibody-antigen complex results in an increase in turbidity at 600nm.By constructing the standard curve, the concentration of Myeloperoxidase can be determined.

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References
  • Leckie MJ, Gomma AH, Purcell IF, et al. Automated quantitationof peripheral blood neutrophil activationin patients with myocardial ischaemia. Int J Cardiol, 2004,95:307-313.
  • Malech HL, Nauseef WM. Primary inherited defects in neutrophil function: etiology and treatment. Semin Hematol,1997,34:279-290.
  • Tiruppathi C, Naqvi T,Wu YB, et al. Albumin mediates the transcytosis of myeloperoxidase by means of caveolae in endothelial cells[J], Proc Natl Acad Sci USA,2004, 101(20):7699-7704
  • Meuwese M C,Stroes E S,Hazen S L,et al.Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals:the EPIC Norfolk Prospective Population Study[J].JAm Coll Cardiol.2007,50(2):159—165.
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