Magnesium Assay Kit (Mg)
For the quantitative in vitro determination of Magnesium in human serum.
Magnesium is one of the major intracellular cations in the body. Its action is closely related to that of calcium. Magnesium deficiency, hypomagnesaemia can result in various neuromuscular disorders, weakness, tremors, tetany and convulsions. It is associated with hypocalcaeia, intravenous therapy, diabetes mellitus, alcoholism, dialysis and pregnancy. Increased serum magnesium levels are associated with dehydration, severe diabetic acidosis and Addison’s Disease. Conditions that interfere with glomerular filtration as in renal failure result in retention of magnesium and hence elevation of serum levels.
Magnesium ions react with xylidyl blue in an alkaline medium to form a water soluble purple-red chelate, the colour intensity of which is proportional to the concentration of magnesium in the sample. Calcium is excluded from the reaction by complexing with EGTA.
- Sunahara , et al,. United States Patent(5108905), Method of assaying magnesium in human body fluid, April 28, 1992
- Kondou ,et al,. United States Patent(5,683,889), Reagent for measurement of magnesium ion, November 4, 1997
- Murachi ,et al,. United States Patent(4778754), Reagent for determining the amount of magnesium ions, October 18, 1988
- Fischer ,et al,. United States Patent(4275031), Agent and process for carrying out colorimetric or photometric determinations, June 23, 1981
- Furuta ,et al,. United States Patent(5968833),Test piece and method of use for measuring magnesium in biological fluid, October 19, 1999.