Lipoprotein (a) Assay Kit Lp(a)
For the in vitro quantitative determination of Lipoprotein (a) in serum or plasma.
Product Features
Lipoprotein (a) determination is intended for use in conjunction with clinical evaluation, patient risk assessment and other lipid tests to evaluate disorders of lipid metabolism and to assess coronary heart disease in specific populations.
Assay Principle
Sample is reacted with a buffer and anti-Lp(a) coated latex. The formation of the antibody-antigen complex during the reaction results in an increase in turbidity, the extent of which is measured as the amount of light absorbed at 600 nm. By constructing a standard curve from the absorbance of the standards, Lp(a) concentration of sample can be determined.
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References
- Tietz NW Clinical Guide to Laboratory Tests. Philadelphia, Pa: WB Sanders, 1995: 442 – 444.
- Marcovina, S.M., Albers, J.J., Wijsman, E., Zhang, Z., Chapman, N.H. and Kennedy, H. (1996). Differences in Lp (a) concentrations and apo (a) polymorphs between black and white Americans. Journal of Lipid Research 37: 2569 – 2585
- Lothar Thomas. Clinical Laboratory Diagnostics. 1st Edition. TH Books.
- Kronenberg, Lobentanz, Konig, Utermann and Dieplinger; (1994), Journal of Lipid Research 35:1318-1328.
- Marcovina, S.M., Albers, J.J., Scanu, A.M. et al. (2000) Use of a Reference Material Proposed by the International Federation of Clinical Chemistry and Laboratory Medicine to Evaluate Analytical Methods for the Determination of Plasma Lipoprotein (a). Clinical Chemistry46: (12) 1956 – 1967
- Jenner, J.L., Ordovas, J.m., Lamon-Fava, S. et al. (1993). Effects of Age, Sex and Menopausal Status on Plasma Lipoprotein (a) Levels. The Framingham Offspring Study. Circulation 87: 1135 – 1141.
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