Ferritin Assay Kit (FER)
For the in vitro quantitative determination of Ferritin in serum andplasma.
Ferritin is an iron-containing protein with a molecular weight of approximately 450,000. It is found mainly in the human liver and spleen, where its function is to eliminate and store iron in the body, and is also found in small amounts in human serum. This amount varies according to the movement of iron in the body, and hepatitis and malignant tumors, may be seen to increase due to cell destruction or tumor cell production, independent of iron reserves. Consequently, the measurement of ferritin is considered to be useful in the diagnosis, treatment, assessment of disease progression, and postoperative prognosis for abnormality in iron metabolism such as iron deficiency anemia and hyperferremia as well as hepatitis and malignant tumors.
When an antigen-antibody reaction occurs between ferritin ina sampleandanti-ferritinantibodywhichhasbeenbound to latex particles, agglutination results. This agglutination is detected as an absorbance change, with the magnitude of the change being proportional to the quantity of ferritin in the sample.The actual concentration is then determined by interpolation from a calibration curve prepared from calibrators of known concentration.