Epidermal FABP (FABP5) Human ELISA

Human fatty acid binding protein EFABP is a 15 kD member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to bind fatty acids and related compounds ( bile acids or retinoids). in an internal cavity. The fatty acid binding proteins aP2 (fatty acid binding protein [FABP]-4) and mal1 (EFABP) are closely related and both are expressed in adipocytes. Absence of EFABP/mal1 resulted in increased systemic insulin sensitivity in two models of obesity and insulin resistance. Adipocytes isolated from mal1-deficient mice also exhibited enhanced insulin-stimulated glucose transport capacity. In contrast, mice expressing high levels of mal1 in adipose tissue display reduced systemic insulin sensitivity.

Features

• It is intended for research use only
• The total assay time is less than 3 hours
• The kit measures total EFABP in serum, plasma (EDTA, heparin), urine, and breast milk
• Assay format is 96 wells
• Standard is a recombinant protein
• Components of the kit are provided ready to use, concentrated or lyophilized

Research topic

Cardiovascular disease, Diabetology – Other Relevant Products, Energy metabolism and body weight regulation, Oncology