D-Dimer Assay Kit (D-D)
For the in vitro quantitative determination of D-Dimer in serum or plasma.
Product Features
D-Dimer containing moieties are formed by plasmin degradation of factor XIIIa cross linked fibrin. Elevated levels of D-Dimer are found in clinical conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE) and disseminated intravascular coagulation (DIC). D-Dimer levels rise during pregnancy and high levels are associated with complications.
Assay Principle
D-Dimer in serum or plasma reacts with antibody specific for human D-Dimer,which is coated with latex partical. The formation of antibody-antigen complex results in a increase of absorbance at 540nm.
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References
- Shisou, K, Fujimaki, M: Fibrin/Fibrinogen degradation products (FDP) , Japanese Society of Laboratory Medicine (598): 892, 1989
- Rylatt D.B.,et al:An immunoassay for human D dimer using monoclonal antibodies. Thromb. Res., 31(6):767,1983.
- Shisou, K, Fujimaki, M: Assay of Stabilized FDP, Japan Society on Thrombosis and Homeostasis, 2(1): 82, 1991
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