Creatinine Assay Kit (CRE)
For the in vitro quantitative determination of Creatinine in serum, plasma or urine.
Product Features
As a measure of kidney function, clinically the estimation of serum creatinine is considered superior to that of blood urea nitrogen, and the determination of the endogenous creatinine clearance is the commonly employed clinical measure of glomerular filtration rate.
Assay Principle
Creatinine in the samples reacts with the picric acid in alkaline buffer solution to form a water soluble red compound, the colour intensity of which is proportional to the concentration of creatinine in the sample.
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References
- Osberg IM, Hammond KB. A solution to the problem of bilirubin interference with the kinetic Jaffe method for serum creatinine. Clin Chem 1978;24:1196-7.
- Bowers LD, Wong ET. Kinetic serum creatinine assays. II. A critical evaluation and review. Clin Chem1980;26:555-61.
- Bowers LD. Kinetic serum creatinine assays. The role of various factors in determining specificity. Clin Chem198026:551-.
- Glick JH, Brown DM, Crocker CL, Haisten SM,Peine CA. Preparation of reagents for use with the Beckman Astra-8. Clin Chem
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