Ceruloplasmin

This product is used on NEPHSTAR® protein analysis system for quantitative determination of human Ceruloplasmin (CER) in serum


Catalog No
Product Catalog No: DK018

Pack Size:
Pack Size:
Pack Size:
Pack Size:
Code Name Volume/Quantity
Product Catalog No: DA018 Pack Size: CER Antiserum Pack Size: 1×2.0 ml
Product Catalog No: DB018 Pack Size: CER Reaction buffer Pack Size: 1×25.0 mL
Product Catalog No: DC018 Pack Size: CER Magnetic card Pack Size: 1
Product Catalog No: DM018 Pack Size: CER Control Pack Size: 1×0.3mL

Product Code: CER
Category:
Summary

Ceruloplasmin is a copper oxidase enzyme, possible important in regulating the ionic state of iron and other metallic ions. Levels are decreased in hepatoenticular degeneration or Wilson’s disease and Menke’s Kinky hear syndrome. Levels are elevated by the acute phase response and particularly by estrogens.

Test Principle

Immunonephelometry is applied. This method involves measuring the light scattered by insoluble complexes formed by reaction between specific protein in samples and its respective antiserum, and the amount of scattered light is directly proportional to the concentration of the protein under condition that antiserum is in excess. Concentrations are automatically calculated by reference to a calibration curve stored in the instrument.

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    References

    1. Bablok W et al. General Regression Procedure for Method Transformation. J Clin Chem Biochem 1988; 26:783-790

    2. Deutsch E, Geyer G, Wenger R, Laboratoriumsmedizin. Normalbereich der Ergebnisse und Interpretation abnormer Befunde, 3rd ed. Basel/Munich: Karger 1992.

    3. Poulik, M. D., and Weiss, M. L., in F. W. Putman, Editor, “The Plasma Proteins”, vol. 2 second Edition, Academic Press, New York, pp. 52 – 108.

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