Blood C-Reactive Protein

CRP is synthesized in liver and consists of five identical polypeptide chains forming a five-membered ring of molecular weight of 120 kD. CRP is one of the most characteristic acute-phase proteins and is considered as a reliable indicator of disease activity in various clinical conditions. Its concentration in blood increases rapidly by as much as 1000-fold upon exposure to various inflammatory stimuli. CRP has been used successfully for clinical diagnosis and monitoring of a variety of infections and diseases, including infections caused by bacteria, fungi, and viruses ; intercurrent infections in leukemia and systemic lupus erythematosus; noninfectious inflammatory diseases such as rheumatoid arthritis; and diseases with cellular necrosis such as myocardial infarction. Measurements of CRP are especially useful in distinguishing viral from bacterial infections. Traditional method of measuring CRP concentration is using serum as sample, which means more steps and more time to attain the goal. Goldsite therefore develops this Blood CRP kit using whole blood as testing sample. With this kit CRP concentration can be measured with venous blood or capillary blood and the procedure is simpler and quicker.