Aldosterone ELISA
Aldosterone is a potent mineral corticoid whose synthesis and release are controlled by the renin-angiotensin system of the body. Aldosterone promotes the reabsorption of sodium in the distal tubules of the kidney resulting in potassium secretion along with sodium retention, which controls the circulating blood volume. Chronic overproduction and secretion of aldosterone leads to hypertension. Measurement of aldosterone levels in serum in conjunction with plasma renin levels can be used to differentiate between primary and secondary aldosteronism.
Type
Competitive ELISA
Applications
Serum, Urine, Plasma
Sample Requirements
50 µL
Storage/Expiration
Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
Calibration Range
15–1000 pg/ml
Limit of Detection
9.1 pg/ml
– Mori Y, Shimizu H, Kushima H, Hiromura M, Terasaki M, Tanaka M, Osaki A, Hirano T. Increased blood pressure in nesfatin/nuclebindin-2-transgenic mice. Hypertens Res. 2017 Apr 27. doi: 10.1038/hr.2017.61