α-Fetoprotein Assay Kit (AFP)

For the quantitative in vitro of AFP in human serum or plasma. Fetoprotein is the most important diagnostic indicators of primary liver cancer, mainly used for patients with primary liver cancer has been diagnosed with dynamic monitoring to determine disease progression or treatment of secondary effects.



Product Catalog Number Packaging Method/Format
Product Catalog No: Kit (45 Ml) Pack Size: GB8020G Pack Size: R1: 2 × 15 ml
R2: 1 × 15 ml
Pack Size: Latex Immunoturbidimetric
Product Catalog No: Kit (45 Ml) Pack Size: GS8021G Pack Size: R1: 2 × 15 ml
R2: 1 × 15 ml
Product Catalog No: Kit (45 Ml) Pack Size: GT8021G Pack Size: R1: 2 × 15 ml
R2: 1 × 15 ml
Product Catalog No: Calibrator Pack Size: GC-AFP-L Pack Size: 6×1 ml
Pack Size:
Product Catalog No: Control Pack Size: GQ-AFP-L Pack Size: 2×1 ml
Pack Size:

Category:
Product Features

Alpha-fetoprotein (AFP) is a fetuin, which contains 3% sugar and molecular weight is about 70,000. AFP is abound in the fetal period , decreased rapidly after birth, the serum level is minimal in normal person. Fetoprotein is the most important diagnostic indicators of primary liver cancer, for it sharply rises in patients with primary liver cancer. Diagnosis of hepato cellular carcinoma (HCC) by Fetoprotein, not only to observe its absolute value, but also to observe the dynamic changes, the dynamic changes of AFP are: sustained high concentration type : diagnostic specificity is high, the majority of them are middle or advanced liver cancer; saddle -shaped, which is rare,but easily missed. The liver cancer often have significant performance when AFP elevated in the peak of the saddle; 3)a sharp rise type : which is more common in the higher degree of malignancy tumors, spread rapidly, but accidentally AFP rise sharply, accompany decreased rapidly with ALT elevated acute hepatic necrosis; a steady increase type , regular inspection, steadily increase, is with most diagnostic value; repeated wave type , which is common in acute and chronic benign liver disease. And AFP concentration elevating and going down in human serum is with great value in disease development, efficiency of liver cancer recurrence and observation.

Assay Principle

AFP reacts with Hypersensitive AFP antibody latex particles reagent, agglutination reaction occurs, detecting the absorbance at a wavelength of 700 nm, the degree of variation in the sample is with direct proportion of AFP.

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References
  • Rong Luo,Zhuocheng Li,Jianxiong Chen, Xiongying. Dynamic changes and clinical significance of serum mAST / AST ratio in patients with liver.Journal of Tropical Medicine, 2008, 6( 8) :567-569.
  • Lindstrom,F.,Diehl,.h.,Anal.Chem.1960 32:1123
  • Gindler,E.M.,HethD.A.,ClinChem1987.17:662
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