Comprehensive Metabolic Panel
The Piccolo® Comprehensive Metabolic Panel, used with the Piccolo® blood chemistry analyzer or the Piccolo Xpress® chemistry analyzer, is intended to be used for the in vitro quantitative determination of alanine aminotransferase (ALT), albumin, alkaline phosphatase (ALP), aspartate aminotransferase (AST), calcium, chloride, creatinine, glucose, potassium, sodium, total bilirubin, total carbon dioxide, total protein, and blood urea nitrogen (BUN) in heparinized whole blood, heparinized plasma, or serum in a clinical laboratory setting or point-of-care location.
The Piccolo Comprehensive Metabolic Panel and the Piccolo blood chemistry analyzer or the Piccolo Xpress chemistry analyzer comprise an in vitro diagnostic system that aids the physician in diagnosing the following disorders:
| Alanine Aminotransferase (ALT) | Liver diseases; including viral hepatitis and cirrhosis. |
|---|---|
|
Albumin |
Liver and kidney diseases. |
| Alkaline phosphatase (ALP) | Liver, bone, parathyroid and intestinal diseases. |
| Aspartate Aminotransferase (AST) | Liver disease including hepatitis and viral jaundice, shock. |
| Calcium | Parathyroid, bone and chronic renal diseases; tetany. |
| Chloride | Dehydration, prolonged diarrhea and vomiting, renal tubular disease, hyperparathyroidism, burns, salt-losing renal diseases, overhydration and thiazide therapy. |
| Creatine Kinase | Myocardial infarction, progressive muscular dystrophy, dermatomyositis, rhabdomyolysis due to drug ingestion, hyperosmolality, autoimmune disease, delirium tremens, convulsions, Crush syndrome, hypothyroidism, surgery, severe exercise, intramuscular injection, physical inactivity, decreased muscle mass. |
| Creatinine | Renal disease and monitoring of renal dialysis. |
| Glucose | Carbohydrate metabolism disorders, including adult and juvenile diabetes mellitus and hypoglycemia. |
| Potassium | Renal glomerular or tubular disease, adrenocortical insufficiency, diabetic ketacidosis, excessive intravenous potassium therapy, sepsis, panhypopituitarism, in vitro hemolysis, hyperaldosteronism, malnutrition, hyperinsulinism, metabolic alkalosis and gastrointestinal loss. |
| Sodium | Dehydration, diabetes insipidus, loss of hypotonic gastrointestinal fluids, salt poisoning, selective depression of sense of thirst, skin losses, burns, sweating, hyperaldosteronism, CNS disorders, dilutional, depletional and delusional hyponatremia and syndrome of inappropriate ADH secretion. |
| Total bilirubin | Liver disorders, including hepatitis and gall bladder obstruction; jaundice. |
| Total carbon dioxide | Primary metabolic alkalosis and acidosis and primary respiratory alkalosis and acidosis. |
| Total protein | Liver, kidney, bone marrow diseases; metabolic and nutritional disorders. |
| Blood Urea Nitrogen (BUN) | Renal and metabolic diseases. |