Pyruvate Assay Kit (PYR)

PYR Mainly used in clinical diagnosis of diabetic ketoacidosis. Pyruvate is the major intermediates for glucose catabolism and anabolism, pyruvate is the product of glycolysis, to oxidize to CO2 and H2O by citric acid cycle, keep the blood of L / P ratio at about 9. When the body is under hypoxic metabolism, pyruvate is reduced to lactate, L / P increased. More severe hypoxia, more obvious of the L / P increasing. According to L / P ratio, the severity of circulatory failure can be speculated. Vitamin B1 deficiency, chronic alcoholism, chronic pulmonary heart disease, diabetes and ketoacidosis can cause pyruvate level elevate in blood.