Retinol Binding Protein Assay Kit (RBP)

Retinol-binding protein is a sensitive index to reflect the nutritional status of the body, especially protein – calorie malnutrition. Visceral protein is a conventional laboratory indicators of protein – energy malnutrition, but retinol-binding protein can make a faster response. RBP is mainly synthesized in the liver. The change of serum RBP is related with liver disease and is influenced by the emergence of liver disease and severity of the impact. The concentration of RBP is significantly decreased in liver disease, cirrhosis and acute, chronic hepatitis. RBP can be used as a indicator of the early diagnosis of renal tubular injury. Retinol-binding protein is stable in the urine, not easily broken down, and not disturbed by pH and blood pressure etc. When the renal proximal tubule is injured, urinary displacement increases significantly, so the increasing of RBP in urine can be used as a marker of therenal proximal tubule injury. When kidney filtration function is injured, the concentration of blood RBP increase. So RBP concentration in the blood or urine can be used clinically as an ideal marker of renal function.