D-Dimer ( D Dimer Assay Kit )
The quantitative determinationin D-Demer in serum or plasma.
In vitro test for the quantitative determination of D-Dimer in human plasma. When D-Dimer values below the cutoff are obtained, deep venous thrombosis (DVT) of the lower limb and pulmonary embolism (PE) can be excluded with high sensitivity In disseminated intravasal coagulation (DIC)/consumptive coagulopathy, fibrin degradation products are a sensitive marker. Monitoring the fibrin-specific degradation products can be used to confirm or refute a tentative diagnosis, estimate the potential risk for patients with existing DIC and monitor an initiated therapy.
Latex particles of uniform size are coated with monoclonal antibodies to the D-Dimer epitope. The antigen/antibody complexes produced by the addition of samples containing D-Dimer lead to an increase in the turbidity of the test reactants. The change of absorbance with time is dependent on the concentration of D-Dimer epitopes in the sample. The precipitate is determined turbidimetrically.
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