Calprotectin (Serum)

The described Calprotectin ELISA kit is intended for measurement of (MRP8/14, S100A8/A9) in serum, EDTA-plasma and urine.


Catalog No Size
Product Catalog No: EIA-5111 Pack Size: 96 Wells

Pack Size:
Pack Size:
Pack Size:
Pack Size:

Category:
Summary

Calprotectin is a calcium-binding protein secreted predominantly by neutrophils and monocytes. The heterocomplex consists of the two proteins, S100A8 (calgranulin A) and S100A9 (calgranulin B), also designated as MRP8 and MRP14, respectively.

Order Enquiry

Order Enquiry Form

References
  • Striz I, Trebichavsky I: Calprotectin – a pleiotropic molecule in acute and chronic inflammation. Physiol Res 2004, 53: 245-253.
  • Yui S, Nakatani Y, Mikami M: Calprotectin (S100A8/S100A9), an inflammatory protein complex from neutrophils with a broad apoptosis-inducing activity. Biol Pharm Bull 2003, 26: 753-760.
  • Odink K, Cerletti N, Bruggen J, Clerc RG, Tarcsay L, Zwadlo G et al.: Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis. Nature 1987, 330: 80-82.
  • Wilkinson MM, Busuttil A, Hayward C, Brock DJ, Dorin JR, Van H, V: Expression pattern of two related cystic fibrosis-associated calcium-binding proteins in normal and abnormal tissues. J Cell Sci 1988, 91 ( Pt 2): 221-230.
  • Muller F, Froland SS, Aukrust P, Fagerhol MK: Elevated serum calprotectin levels in HIV-infected patients: the calprotectin response during ZDV treatment is associated with clinical events. J Acquir Immune Defic Syndr 1994, 7: 931-939.
  • Hermani A et al. Calcium-Binding Proteins S100A8 and S100A9 as novel diagnostic markers in human prostate cancer. Clin Cancer Res 2005, 11: 5146-5152.
Enquiry